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Uganda launches trial vaccine to combat Sudan strain of Ebola

Matooke Republic by Matooke Republic
February 4, 2025
in Health
Reading Time: 2 mins read
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In response to the recent death of a nurse in Kampala, the Ministry of Health, in collaboration with the World Health Organization (WHO), has initiated a trial Ebola vaccine targeting the Sudan strain.

This initiative aims to protect individuals at high risk, particularly those who had direct contact with the deceased healthcare worker.

Uganda has received 2,460 doses of the trial vaccine from WHO, and administration has commenced on a voluntary basis, requiring informed consent from recipients. The launch event happened on Monday at Mulago Hospital.

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Professor Bruce Kirenga, Principal Investigator of the trial, highlighted the unique nature of the vaccine.

“Each Ebola strain requires its own vaccine. The vaccines developed for the Zaire strain are ineffective against the Sudan strain, which we are currently facing,” he explained.

The first recipient of the vaccine, a close contact of the deceased nurse, will be closely monitored over the next 28 days to evaluate its effectiveness and potential side effects.

Dr. Mike Ryan, Deputy Director General of WHO, expressed confidence in Uganda’s ability to manage the outbreak, citing the nation’s past success in handling similar crises.

“This marks Uganda’s eighth Ebola outbreak, and I have personally witnessed the country’s resilience and commitment to controlling such epidemics,” Dr. Ryan stated.

Health authorities have identified 234 contacts linked to the deceased nurse, with 45 classified as high-risk individuals, including 34 healthcare workers and 11 family members. Meanwhile, two additional confirmed cases are receiving treatment at the Mulago Isolation Centre.

Ebola is a highly infectious disease that spreads through direct contact with bodily fluids of infected individuals. Unlike the Zaire strain, which has an approved vaccine, no licensed vaccine currently exists for the Sudan strain, making this trial a crucial step in fighting the outbreak.

The Ministry of Health urges the public to remain vigilant and report any symptoms such as fever, vomiting, unexplained bleeding, or muscle pain. Authorities continue to implement containment measures to curb further spread.

The 32-year-old nurse who tragically succumbed to the virus last week experienced severe symptoms, including high fever, breathing difficulties, and unexplained bleeding.

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Tags: ebolaEbola vaccineMinistry of HealthWorld Health Organisation
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